Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

@inproceedings{Shikhagaie2017Neuropilin1IE,
  title={Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates},
  author={Medya Mara Shikhagaie and {\AA}sa K. Bj{\"o}rklund and Jenny Mj{\"o}sberg and Jonas S Erjef{\"a}lt and Anne S Cornelissen and Xavier Romero Ros and Suzanne M Bal and Jasper J Koning and Reina E Mebius and Michiko Matsui Mori and M{\'e}lanie Bruchard and Bianca Blom and Hergen Spits},
  booktitle={Cell reports},
  year={2017}
}
Here, we characterize a subset of ILC3s that express Neuropilin1 (NRP1) and are present in lymphoid tissues, but not in the peripheral blood or skin. NRP1+ group 3 innate lymphoid cells (ILC3s) display in vitro lymphoid tissue inducer (LTi) activity. In agreement with this, NRP1+ ILC3s are mainly located in proximity to high endothelial venules (HEVs) and express cell surface molecules involved in lymphocyte migration in secondary lymphoid tissues via HEVs. NRP1 was also expressed on mouse… CONTINUE READING
BETA
2
Twitter Mentions

Citations

Publications citing this paper.
SHOWING 1-10 OF 13 CITATIONS

Innate Lymphoid Cells (ILCs): Cytokine Hubs Regulating Immunity and Tissue Homeostasis.

  • Cold Spring Harbor perspectives in biology
  • 2018
VIEW 8 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

The roles for innate lymphoid cells in the human immune system

VIEW 7 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Chapter 7 Innate Lymphoid Cells ( Non ‐ NK ILCs )

Ahmet Eken, Hamiyet Donmez ‐ Altuntas
  • 2018
VIEW 1 EXCERPT
CITES BACKGROUND

Role of inflammatory cells in airway remodeling in COPD

  • International journal of chronic obstructive pulmonary disease
  • 2018
VIEW 1 EXCERPT

Similar Papers

Loading similar papers…