Neurophysiology and neural engineering: a review.

@article{Prochazka2017NeurophysiologyAN,
  title={Neurophysiology and neural engineering: a review.},
  author={Arthur Prochazka},
  journal={Journal of neurophysiology},
  year={2017},
  volume={118 2},
  pages={
          1292-1309
        }
}
  • A. Prochazka
  • Published 1 August 2017
  • Biology
  • Journal of neurophysiology
Neurophysiology is the branch of physiology concerned with understanding the function of neural systems. Neural engineering (also known as neuroengineering) is a discipline within biomedical engineering that uses engineering techniques to understand, repair, replace, enhance, or otherwise exploit the properties and functions of neural systems. In most cases neural engineering involves the development of an interface between electronic devices and living neural tissue. This review describes the… 

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References

SHOWING 1-10 OF 254 REFERENCES
Mechanisms of Electrical Stimulation with Neural Prostheses
TLDR
Analysis with the generalized activating function, computer simulations of the nonlinear neural membrane behavior together with experimental and clinical data analysis enlighten the understanding of artificial firing patterns influenced by neural prostheses.
Neural Prostheses for Neurotrauma
TLDR
The basic components and design of NPs and their mechanisms of action are considered, including the control of the urinary bladder, which is a major area of NP research and development.
Challenges and Opportunities in Restoring Function After Paralysis
TLDR
Techniques that combine approaches are likely to be the most effective means for restoring function, for example combining regeneration and neural plasticity to maximize voluntary activity, combined with neural prostheses to augment the voluntary activity to functional levels of performance.
Restoring cortical control of functional movement in a human with quadriplegia
TLDR
This is the first demonstration of successful control of muscle activation using intracortically recorded signals in a paralysed human, and has significant implications in advancing neuroprosthetic technology for people worldwide living with the effects of paralysis.
The neuromechanical tuning hypothesis.
Behavioral assessment of sensitivity to intracortical microstimulation of primate somatosensory cortex
TLDR
The ability of monkeys to detect and discriminate trains of electrical pulses delivered to their somatosensory cortex through chronically implanted electrode arrays is investigated and it is shown that artificial touch is highly dependent on various features of the electrical stimuli.
Sensory control of normal movement and of movement aided by neural prostheses
TLDR
In spite of the dissimilarities, parallels can be found between feedback control in neuroprostheses and in animals and this can provide surprising insights in both directions.
Using an Artificial Neural Bypass to Restore Cortical Control of Rhythmic Movements in a Human with Quadriplegia
TLDR
An artificial neural bypass technology is shown that decodes cortical activity and emulates spinal cord CPG function allowing volitional rhythmic hand movement and a quadriplegic participant was able to initiate, sustain, and switch between rhythmic and discrete finger movements, using his thoughts alone.
Spinal Cord Microstimulation Generates Functional Limb Movements in Chronically Implanted Cats
TLDR
It is demonstrated that microwires implanted in the spinal cord remain stably in place and stimulation through these electrodes produces strong, controllable movements, providing a promising basis for the use of spinal cord neuroprostheses in restoring mobility following spinal cord injury.
...
...