Neurophysiological approach to central pain modulation in primary headaches

@inproceedings{Rossi2005NeurophysiologicalAT,
  title={Neurophysiological approach to central pain modulation in primary headaches},
  author={Paolo Rossi and Mariano Serrao and Alison Perrotta and Francesco Pierelli and Giorgio Sandrini and Giuseppe Nappi},
  booktitle={The Journal of Headache and Pain},
  year={2005}
}
The study of CNS painmodulating pathways has led to important discoveries about the role of central nociceptive structures such as PAG and hypothalamus in the pathophysiology of episodic and chronic primary headaches. Functional neuroimaging studies have revealed that primary headaches are characterised by different patterns of activation of central pain modulatory structures. A future model of headache pathophysiology investigating the contribution of CNS pain–modulating pathways will probably… CONTINUE READING

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