Neurophysiologic evidence for a central sensitization in patients with fibromyalgia.

  title={Neurophysiologic evidence for a central sensitization in patients with fibromyalgia.},
  author={Jules A. Desmeules and Christine Cedraschi and Elisabetta Rapiti and E. V. Baumgartner and Axel Finckh and P Cohen and P Dayer and T. L. Vischer},
  journal={Arthritis and rheumatism},
  volume={48 5},
OBJECTIVE To determine whether abnormalities of peripheral and central nociceptive sensory input processing exist outside areas of spontaneous pain in patients with fibromyalgia (FM) as compared with controls, by using quantitative sensory testing (QST) and a neurophysiologic paradigm independent from subjective reports. METHODS A total of 164 outpatients with FM who were attending a self-management program were invited to participate in the study. Data for 85 patients were available and were… 

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