Neuropharmacological studies in rodents on the action of RX 781094, a new selective alpha 2-adrenoceptor antagonist.

@article{Dettmar1983NeuropharmacologicalSI,
  title={Neuropharmacological studies in rodents on the action of RX 781094, a new selective alpha 2-adrenoceptor antagonist.},
  author={Peter W. Dettmar and Alfred Lynn and Ian F. Tulloch},
  journal={Neuropharmacology},
  year={1983},
  volume={22 6},
  pages={729-37}
}
Several neuropharmacological effects of RX 781094, a new selective alpha 2-adrenoceptor antagonist, have been investigated in rodents. In rats, RX 781094 (0.1-1.0 mg kg-1, i.v.) produced a rapid dose-related reversal of cortical EEG synchronisation and behavioural sedation, induced by clonidine or the more selective alpha 2-adrenoceptor agonist, guanoxabenz… CONTINUE READING