Neuropharmacological profile of FrPbAII, purified from the venom of the social spider Parawixia bistriata (Araneae, Araneidae), in Wistar rats.

Abstract

The aims of the present study were to investigate the anticonvulsant activity and behavioral toxicity of FrPbAII using freely moving Wistar rats. Moreover, the effectiveness of this compound against chemical convulsants was compared to that of the inhibitor of the GABAergic uptake, nipecotic acid. Our results show that FrPbAII was effective against seizures… (More)

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@article{Gelfuso2007NeuropharmacologicalPO, title={Neuropharmacological profile of FrPbAII, purified from the venom of the social spider Parawixia bistriata (Araneae, Araneidae), in Wistar rats.}, author={{\'E}rica Aparecida Gelfuso and Alexandra Ol{\'i}mpio Siqueira Cunha and M{\'a}rcia Renata Mortari and Jos{\'e} Luiz Liberato and Karina Haddad Paraventi and Ren{\^e} de Oliveira Beleboni and Joaquim Coutinho-Netto and Norberto Peporine Lopes and Wagner Ferreira Dos Santos}, journal={Life sciences}, year={2007}, volume={80 6}, pages={566-72} }