Neuropeptides shaping the central nervous system development: Spatiotemporal actions of VIP and PACAP through complementary signaling pathways

  title={Neuropeptides shaping the central nervous system development: Spatiotemporal actions of VIP and PACAP through complementary signaling pathways},
  author={Tando Maduna and V. Leli{\`e}vre},
  journal={Journal of Neuroscience Research},
  • Tando Maduna, V. Lelièvre
  • Published 2016
  • Biology, Medicine
  • Journal of Neuroscience Research
  • Pituitary adenylate cyclase–activating polypeptide (PACAP) and vasoactive intestinal peptide (VIP) are neuropeptides with wide, complementary, and overlapping distributions in the central and peripheral nervous systems, where they exert important regulatory roles in many physiological processes. VIP and PACAP display a large range of biological cellular targets and functions in the adult nervous system including regulation of neurotransmission and neuroendocrine secretion and neuroprotective… CONTINUE READING
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