Neuropeptides in coelenterates: a review

  title={Neuropeptides in coelenterates: a review},
  author={Cornelis J. P. Grimmelikhuijzen and Delia Graff and Osamu Koizumi and Jane A. Westfall and IAN D. McFARLANE},
Coelenterate neurones produce peptides containing an Arg-Phe-NH2(RF-amide)-like carboxyterminus. RF-amide-like peptides are located in neuronal dense-cored vesicles, indicating that they are released by exocytosis and that they might function as neurotransmitters or neurohormones. Using a radioimmunoassay for the sequence RF-amide, 3 peptides were isolated from the sea anemone Anthopleura elegantissima: < Glu-Gly-Arg-Phe-NH2(Antho-RF-amide), <Glu-Ser-Leu-Arg-Trp-NH2(Antho-RWamide I) and <Glu… CONTINUE READING