Neuropeptides and neuroendocrine hormones in ultraviolet radiation-induced immunosuppression.

  title={Neuropeptides and neuroendocrine hormones in ultraviolet radiation-induced immunosuppression.},
  author={Kristina Seiffert and Richard D Granstein},
  volume={28 1},
Exposure of the skin to ultraviolet radiation (UVR) can lead to deleterious effects such as sunburn, photoaging, and the development of skin cancer. UVR has also been shown to reduce local and systemic immune responses in humans and animals. In the recent past it has become clear that neuropeptides mediate some of the effects of UVR-induced immunosuppression. Among the neuropeptides released from cutaneous nerves after exposure to UVR, calcitonin gene-related peptide (CGRP) has been examined… CONTINUE READING


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