Neuropeptide release influences brain edema formation after diffuse traumatic brain injury.

@article{Vink2003NeuropeptideRI,
  title={Neuropeptide release influences brain edema formation after diffuse traumatic brain injury.},
  author={Robert Vink and Ashley Young and Carol J. Bennett and Xintian Hu and Ciara O Connor and Ibolja Cernak and Alan J. Nimmo},
  journal={Acta neurochirurgica. Supplement},
  year={2003},
  volume={86},
  pages={257-60}
}
The mechanisms associated with edema formation after traumatic brain injury (TBI) have not been fully elucidated. In peripheral tissue injury, the neurogenic component of inflammation plays a significant role in increased vascular permeability and edema formation. However, few studies have examined the role of neuropeptide induced neurogenic inflammation following TBI. Adult male Sprague-Dawley rats were either left untreated, or pre-treated with capsaicin (125 mg/kg s.c.) or equal volume… CONTINUE READING

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