Neuropeptide modulation of single calcium and potassium channels detected with a new patch clamp configuration.

Abstract

Calcium channel activity is crucial for secretion and synaptic transmission, but it has been difficult to study Ca2+ channel modulation because survival and regulation of some of these channels require cytoplasmic constituents that are lost with the formation of cell-free patches. Here we report a new patch clamp configuration in which activity and… (More)

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Cite this paper

@article{Levitan1990NeuropeptideMO, title={Neuropeptide modulation of single calcium and potassium channels detected with a new patch clamp configuration.}, author={Edwin S Levitan and R. H Kramer}, journal={Nature}, year={1990}, volume={348 6301}, pages={545-7} }