Neuropeptide families and their receptors: evolutionary perspectives.

  title={Neuropeptide families and their receptors: evolutionary perspectives.},
  author={Charles H. V. Hoyle},
  journal={Brain research},
  volume={848 1-2},
Examination of families of neuropeptides and their receptors can provide information about phyletic relationships and evolutionary processes. Within an individual a given signal molecule may serve many diverse functions, mediated via subtypes of the receptor which may be coupled to their transduction mechanisms in different ways. The rate of evolution of a peptide may reflect or be reflected in the rate of evolution of its receptor. For example, in the neuropeptide Y (NPY) family, pancreatic… CONTINUE READING
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