Neuropeptide and sigma receptors as novel therapeutic targets for the pharmacotherapy of depression.

Abstract

Among the most prevalent of mental illnesses, depression is increasing in incidence in the Western world. It presents with a wide variety of symptoms that involve both the CNS and the periphery. Multiple pharmacological observations led to the development of the monoamine theory as a biological basis for depression, according to which diminished… (More)
DOI: 10.2165/11310830-000000000-00000

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