Neuropeptide Y induced modulation of dopamine synthesis in the striatum.

  title={Neuropeptide Y induced modulation of dopamine synthesis in the striatum.},
  author={Adepero Shola Adewale and Heather Macarthur and Thomas C. Westfall},
  journal={Regulatory peptides},
  volume={129 1-3},
The purpose of the present study was to determine whether the activation of NPY receptors alters catecholamines (CA) synthesis in the central nervous system and, if so, to identify the NPY receptor subtype(s) mediating this effect. Tyrosine hydroxylation, the rate-limiting step in CA synthesis, was assessed by measuring the accumulation of 3,4-dihydroxyphenyalanine (DOPA) by high pressure liquid chromatography coupled to electrochemical detection (HPLC-EC) in rat striatal dices following… CONTINUE READING


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