Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers.

@article{Ekblad1984NeuropeptideYC,
  title={Neuropeptide Y co-exists and co-operates with noradrenaline in perivascular nerve fibers.},
  author={Eva Ekblad and Lars Edvinsson and Claes Wahlestedt and Rolf Uddman and Rolf H{\aa}kanson and Frank Sundler},
  journal={Regulatory peptides},
  year={1984},
  volume={8 3},
  pages={225-35}
}
Neuropeptide Y (NPY)-immunoreactive nerve fibers were numerous around arteries and few around veins. NPY probably co-exists with noradrenaline in such fibers since chemical or surgical sympathectomy eliminated both NPY and noradrenaline from perivascular nerve fibers and since double staining demonstrated dopamine-beta-hydroxylase, the enzyme that catalyzes the conversion of dopamine to noradrenaline, and NPY in the same perivascular nerve fibers. Studies on isolated blood vessels indicated… CONTINUE READING

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