Neuropeptide Y blocks a calcium current in C cells of bullfrog sympathetic ganglia.


The effects of neuropeptide Y (NPY) on the Ca2+ current of enzymatically dispersed neuronal somata from bullfrog paravertebral sympathetic ganglia were investigated using the patch-clamp technique. In C neurons, NPY induced a concentration-dependent decrease in the amplitude of the Ca2+ current and induced a slow biphasic current rising phase. Upon removal… (More)