Neuropeptide Y Stimulates Proliferation and Migration of Vascular Smooth Muscle Cells from Pregnancy Hypertensive Rats via Y1 and Y5 Receptors

@inproceedings{Zhang2015NeuropeptideYS,
  title={Neuropeptide Y Stimulates Proliferation and Migration of Vascular Smooth Muscle Cells from Pregnancy Hypertensive Rats via Y1 and Y5 Receptors},
  author={Ping Zhang and Ying-Xin Qi and Qing-Ping Yao and Xiao-Hu Chen and Guo-liang Wang and Bao-rong Shen and Yue Han and Li-Zhi Gao and Zong-lai Jiang and Yingxiao Wang},
  booktitle={PloS one},
  year={2015}
}
The increased proliferation and migration of vascular smooth muscle cells (VSMCs) play important roles in pathophysiological remodeling of arteries during hypertension in pregnancy. However, the mechanisms involved in this process remain unclear. We hypothesized that Neuropeptide Y (NPY), which is a potent mitogenic peptide, participates in modulating proliferation and migration of VSMCs during hypertension in pregnancy. Using pregnant hypertensive rats, induced by intraperitoneal injection of… CONTINUE READING
5 Citations
43 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 43 references

Similar Papers

Loading similar papers…