Neuropeptide Y Is Produced by Adipose Tissue Macrophages and Regulates Obesity-Induced Inflammation

@inproceedings{Singer2013NeuropeptideYI,
  title={Neuropeptide Y Is Produced by Adipose Tissue Macrophages and Regulates Obesity-Induced Inflammation},
  author={Kanakadurga Singer and David L Morris and Kelsie E. Oatmen and Tianyi Wang and Jennifer Delproposto and Taleen A Mergian and Kae Won Cho and Carey N Lumeng},
  booktitle={PloS one},
  year={2013}
}
Neuropeptide Y (NPY) is induced in peripheral tissues such as adipose tissue with obesity. The mechanism and function of NPY induction in fat are unclear. Given the evidence that NPY can modulate inflammation, we examined the hypothesis that NPY regulates the function of adipose tissue macrophages (ATMs) in response to dietary obesity in mice. NPY was induced by dietary obesity in the stromal vascular cells of visceral fat depots from mice. Surprisingly, the induction of Npy was limited to… CONTINUE READING
21 Citations
53 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 53 references

Intraperitoneal injection of neuropeptide Y (NPY) alters neurotrophin rat hypothalamic levels: Implications for NPY potential role in stress-related disorders

  • F Gelfo, P De Bartolo, P Tirassa, N Croce, C Caltagirone
  • Peptides
  • 2011
1 Excerpt

Similar Papers

Loading similar papers…