Neuropeptide S Counteracts Paradoxical Sleep Deprivation-Induced Anxiety-Like Behavior and Sleep Disturbances

@inproceedings{Xie2018NeuropeptideSC,
  title={Neuropeptide S Counteracts Paradoxical Sleep Deprivation-Induced Anxiety-Like Behavior and Sleep Disturbances},
  author={Jun-Fan Xie and Yu-Feng Shao and Hai-Liang Wang and Can Wang and Guang-Fu Cui and Xiang-Pan Kong and Lin-Xin Wang and Yu-Nong Chen and Chao-Yu Cong and Hai-lin Chen and Yi-ping Hou},
  booktitle={Front. Cell. Neurosci.},
  year={2018}
}
Disturbed sleep is a common subjective complaint among individuals with anxiety disorders. Sleep deprivation increases general and specific anxiety symptoms among healthy individuals. The amygdala is critical for regulating anxiety and also involved in mediating the effects of emotions on sleep. Neuropeptide S (NPS) and NPS receptors (NPSR) are reported as a novel endogenous arousal and anxiolytic system, but it is unclear yet whether this system is involved in anxiety-like behavior and sleep… CONTINUE READING
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