Neuropathophysiology of movement disorders in cerebral palsy.

  title={Neuropathophysiology of movement disorders in cerebral palsy.},
  author={Francis M. Filloux},
  journal={Journal of child neurology},
  volume={11 Suppl 1},
Recent developments in understanding the pathophysiology of disordered motor control in cerebral palsy are reviewed. In spastic cerebral palsy, evidence for abnormal segmental as well as supraspinal control of motor neuron output exists. Impaired Ia inhibition of antagonist muscles has been suggested but recently contested. Evidence also supports the role of decreased presynaptic inhibition of Ia afferents and decreased nonreciprocal Ib inhibition. Furthermore, early cerebral injury results in… CONTINUE READING


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