Neuropathology of white matter lesions in vascular cognitive impairment.

  title={Neuropathology of white matter lesions in vascular cognitive impairment.},
  author={Elisabet Englund},
  journal={Cerebrovascular diseases},
  volume={13 Suppl 2},
The white matter is an important locus for tissue damage in vascular cognitive impairment and white matter lesions often dominate over gray matter changes. The spectrum of ischemic white matter lesions histopathologically represents focal and diffuse lesions, the most common form being the combination of both, in varying proportions. In the combined pathology, the diffuse lesion represents a gradient zone of damage towards surrounding normal tissue and may hold over 200 times the volume of an… CONTINUE READING
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