Neuropathology of tuberous sclerosis.

  title={Neuropathology of tuberous sclerosis.},
  author={Masashi Mizuguchi and Sachio Takashima},
  journal={Brain & development},
  volume={23 7},
In the cerebrum of patients with tuberous sclerosis (TSC), there are three types of nodular lesions: cortical tubers, subcortical heterotopic nodules and subependymal giant cell astrocytomas. Histologically, these hamartias and hamartomas contain abnormal giant cells that show evidence of abnormal differentiation of immature neural cells. Recent… CONTINUE READING