Neuropathology of familial tauopathy.

  title={Neuropathology of familial tauopathy.},
  author={Yoshio Tsuboi},
  journal={Neuropathology : official journal of the Japanese Society of Neuropathology},
  volume={26 5},
  • Yoshio Tsuboi
  • Published 2006 in
    Neuropathology : official journal of the Japanese…
Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) is a hereditary progressive neurodegenerative disorder. FTDP-17 was originally defined in Ann Arbor, Michigan, in 1996. Since then, more than 100 families with FTDP-17 have been described throughout the world, including 18 families identified in Japan. Genetic studies have identified 40 different mutations in the microtubule-associated protein tau (MAPT) gene. The clinical features of FTDP-17 are characterized by… CONTINUE READING

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