Neuropathology of chronic pancreatitis in humans.

  title={Neuropathology of chronic pancreatitis in humans.},
  author={Roger G. Keith and Shaf H Keshavjee and Norbert Kerenyi},
  journal={Canadian journal of surgery. Journal canadien de chirurgie},
  volume={28 3},
To investigate the pathogenesis of pain in chronic pancreatitis, tissue resected from 50 patients with this condition was examined by light microscopy. An examiner, blinded to clinical and pathological data, graded perineural fibrosis, inflammation and the composition of inflammatory infiltrate in 2132 separate perineural fields. Correlation of perineural fibrosis and inflammation grading with alcohol ingestion and pain severity was insignificant. Pain severity did correlate with the timing of… CONTINUE READING
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