Neuropathology in Drosophila membrane excitability mutants.

  title={Neuropathology in Drosophila membrane excitability mutants.},
  author={Tim Fergestad and Barry Ganetzky and Michael J. Palladino},
  volume={172 2},
Mutations affecting ion channels and neuronal membrane excitability have been identified in Drosophila as well as in other organisms and characterized for their acute effects on behavior and neuronal function. However, the long-term effect of these perturbations on the maintenance of neuronal viability has not been studied in detail. Here we perform an initial survey of mutations affecting Na+ channels and K+ channels in Drosophila to investigate their effects on life span and neuronal… CONTINUE READING

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