Neuropathology in Alzheimer's disease: target of pharmacotherapy.

  • Elaine Souder
  • Published 2005 in
    Journal of the American Academy of Nurse…


The pathogenesis of AD is complex and not yet fully understood. A number of factors, including amyloid plaques, NFTs, and inflammatory processes, are likely to contribute to development of the disease. Acetylcholine and glutamate are intimately involved in learning and memory. Hypotheses implicating defects within both neurotransmitter systems in AI) are… (More)