Neuropathological substrates of psychiatric symptoms in prospectively studied patients with autopsy-confirmed dementia with lewy bodies.

@article{Ballard2004NeuropathologicalSO,
  title={Neuropathological substrates of psychiatric symptoms in prospectively studied patients with autopsy-confirmed dementia with lewy bodies.},
  author={Clive G. Ballard and Robin Jacoby and Teodoro del Ser and Muhammad Omer Nadeem Khan and David Gonz{\'a}lez Mu{\~n}oz and Clive Holmes and Zsuzanna Nagy and Elaine K. Perry and Catherine Joachim and Evelyn Jaros and John T. O'Brien and Robert H. Perry and Ian G. McKeith},
  journal={The American journal of psychiatry},
  year={2004},
  volume={161 5},
  pages={843-9}
}
OBJECTIVE This investigation was undertaken to clarify the neuropathological substrates of key psychiatric symptoms in dementia with Lewy bodies. METHOD The authors studied 112 autopsy-confirmed cases of dementia with Lewy bodies in patients who had had annual standardized clinical evaluations until their death. The relationships of persistent psychiatric symptoms (visual hallucinations, delusions, depression) to plaques (Consortium to Establish a Registry for Alzheimer's Disease protocol… CONTINUE READING

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