• DOI:10.1002/HIPO.1067
Corpus ID: 2502525

Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia

@article{Harrison2001NeuropathologicalSO,
  title={Neuropathological studies of synaptic connectivity in the hippocampal formation in schizophrenia},
  author={Paul J. Harrison and S. Eastwood},
  journal={Hippocampus},
  year={2001},
  volume={11}
}

• Paul J. Harrison, S. Eastwood
• Published 2001
• Psychology, Medicine
• Hippocampus

Cytoarchitectural changes in the hippocampal formation have been prominent among the various neuropathological abnormalities reported in schizophrenia. Replicated positive findings include decreased neuronal size and alterations in presynaptic and dendritic markers. These findings, in the absence of neurodegenerative changes, suggest that there are alterations in the neural circuitry in schizophrenia. These may represent the anatomical correlate of the aberrant functional connectivity described… Expand

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