Neuropathogenic SIVsmmFGb genetic diversity and selection-induced tissue-specific compartmentalization during chronic infection and temporal evolution of viral genes in lymphoid tissues and regions of the central nervous system.

Abstract

SIVsmmFGb is a lentivirus swarm that induces neuropathology in over 90% of infected pigtailed macaques and reliably models central nervous system HIV infection in people. We have previously studied SIVsmmFGb genetic diversity and compartmentalization during acute infection, but little is understood about diversity and intertissue compartmentalization during… (More)
DOI: 10.1089/aid.2009.0168

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@article{Reeve2010NeuropathogenicSG, title={Neuropathogenic SIVsmmFGb genetic diversity and selection-induced tissue-specific compartmentalization during chronic infection and temporal evolution of viral genes in lymphoid tissues and regions of the central nervous system.}, author={Aaron B Reeve and Nicholas C. Pearce and Kalpana K Patel and Katherine V Augustus and Francis J. Novembre}, journal={AIDS research and human retroviruses}, year={2010}, volume={26 6}, pages={663-79} }