Neurons regulate Schwann cell genes by diffusible molecules

@article{Bolin1993NeuronsRS,
  title={Neurons regulate Schwann cell genes by diffusible molecules},
  author={Laurel M. Bolin and Eric M. Shooter},
  journal={The Journal of Cell Biology},
  year={1993},
  volume={123},
  pages={237 - 243}
}
Successful peripheral nerve regeneration and functional recovery require the reestablishment of the neuron-Schwann cell relationship in the regenerating rat sciatic nerve, neurons differentially regulate Schwann cell genes. The message for the low-affinity NGF receptor, p75NGFR, is induced in Schwann cells distal to the injury and is repressed as regenerating axons make contact with these cells. The inverse is true for mRNA of the myelin gene P0; expression decreases distal to injury and… CONTINUE READING
Highly Cited
This paper has 42 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

“ Retinoic acid signaling after nerve injury ”

Doret K. Kirsten, Schrage Aus, Hagen Jörg, Mey Prof, H. Wagner
2005
View 2 Excerpts

Rapid axoglial signaling mediated by neuregulin and neurotrophic factors.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2004
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Axonal modulation of myelin gene expression in the peripheral nerve.

Journal of neuroscience research • 1990
View 4 Excerpts
Highly Influenced

Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration and regeneration, role of macrophages

R. Heumann, D. Lindhoim, +5 authors H. Thoenen
Proc. Natl. Acad. Sci. USA • 1987
View 6 Excerpts
Highly Influenced

Axons regulate Schwann cell expression of the POU transcription factor SCIP.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 1994
View 1 Excerpt