Neurons of C1 area mediate cardiovascular responses initiated from ventral medullary surface.

@article{Benarroch1986NeuronsOC,
  title={Neurons of C1 area mediate cardiovascular responses initiated from ventral medullary surface.},
  author={Eduardo Elias Benarroch and Antonio Raffaele Michele Granata and David A. Ruggiero and Dong Ho Park and Donald J. Reis},
  journal={The American journal of physiology},
  year={1986},
  volume={250 5 Pt 2},
  pages={R932-45}
}
We sought to establish whether neurons of the C1 area of the rostral ventrolateral medulla (RVL) mediate changes in arterial pressure and heart rate evoked by topical application of drugs to the ventral medullary surface of the rat. Animals were anesthetized, paralyzed, and ventilated. The ventral surface was mapped with L-glutamate, and a restricted zone was identified from which L-glutamate, as well as kainic acid, bicuculline, strychnine, carbachol, or physostigmine, increased arterial… CONTINUE READING

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