Neurons in Rhesus Monkey Visual Cortex: Systematic Relation between Time of Origin and Eventual Disposition

@article{Raki1974NeuronsIR,
  title={Neurons in Rhesus Monkey Visual Cortex: Systematic Relation between Time of Origin and Eventual Disposition},
  author={Pasko Raki{\'c}},
  journal={Science},
  year={1974},
  volume={183},
  pages={425 - 427}
}
  • P. Rakić
  • Published 1 February 1974
  • Biology
  • Science
Autoradiographic evidence after injection of tritiated thymidine indicates that cell position in the laminae of the monkey visual cortex is systematically related to time of cell orgin. The earliest-formed neurons, destined for the deepest stratum, arise at about embryonic day 45, and the last ones, destined for the outermost cell stratum, form at about day 102; cells of intervening layers are generated at intervening times. No neocortical neurons are produced in the last two prenatal months or… 

Genesis of Visual Connections in the Rhesus Monkey

The basic afferent connections of the visual system in the rhesus monkey are laid down before birth, although the process of segregation of terminals and synaptogenesis continue into postnatal period, which shows characteristically wedge-shaped and topographically organized by midgestation.

Prenatal development of the visual system in rhesus monkey.

  • P. Rakić
  • Biology
    Philosophical transactions of the Royal Society of London. Series B, Biological sciences
  • 1977
Results show that all neurons in the primate visual system have been generated, reached their final positions and formed their basic connections subserving ocular dominance before birth, i.e. before visual experience.

The genesis of efferent connections from the visual cortex of the fetal rhesus monkey

The prenatal development of the cortical projections to the dorsal lateral geniculate nucleus (LGN), superior colliculus (SC) and pulvinar was studied by autoradiography of orthogradely transported

Fates of visual cortical neurons in the ferret after isochronic and heterochronic transplantation

  • SK McConnell
  • Biology
    The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 1988
The experiments described here constitute an attempt to manipulate the fates of newly generated cortical neurons upon transplantation, with results that suggest the possibility that the commitment of a cell to a particular laminar position and set of connections may occur very early on in cortical development.

Cytogenesis in the monkey retina

Time of cell origin in the retina of the rhesus monkey (Macaca mulatto) was studied by plotting the number of heavily radiolabeled nuclei in autoradiograms prepared from 2‐ to 6‐month‐old animals,

Laminar Distribution of Isocortical Neurons Projecting to Occipital Grafts in Neonate and Adult Rats

The data show that afferents to physiologically active grafts originate about equally from both supra- and infragranular cortical layers in newborn subjects and that supragranular neurons contribute only 20 and 1.5% of these inputs in P7 and P120 recipients, respectively.

Functional plasticity in the immature striate cortex of the monkey shown by the [14C]deoxyglucose method.

Autoradiographic representation of the local rates of cerebral glucose utilization and local cerebral functional activity by means of the [14C]deoxyglucose technique reveals the existence of the

Genesis of Topographic and Cellular Diversity in the Primate Retina

The retina in the developing macaque monkey is an unexcelled model system for the analysis of cellular events and the mechanisms that govern formation of the human eye, and the hypothesis that, at early developmental stages, intrinsic mechanisms operating within the retina predominate, while at later stages reciprocal interactions with the visual centers refines the numerical cellular relationships and synaptic architecture is supported.
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