Neurons derived from radial glial cells establish radial units in neocortex

  title={Neurons derived from radial glial cells establish radial units in neocortex},
  author={Stephen C. Noctor and Alexander C. Flint and Tamily A. Weissman and Ryan S. Dammerman and Arnold R. Kriegstein},
The neocortex of the adult brain consists of neurons and glia that are generated by precursor cells of the embryonic ventricular zone. In general, glia are generated after neurons during development, but radial glia are an exception to this rule. Radial glia are generated before neurogenesis and guide neuronal migration. Radial glia are mitotically active throughout neurogenesis, and disappear or become astrocytes when neuronal migration is complete. Although the lineage relationships of… 

Radial glia give rise to adult neural stem cells in the subventricular zone.

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Radial glial origin of the adult neural stem cells in the subventricular zone

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Investigating radial glia in vitro

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Neurogenic radial glial cells in reptile, rodent and human: from mitosis to migration.

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Lineage of radial glia in the chicken optic tectum.

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Radial glia phenotype: Origin, regulation, and transdifferentiation

The perception of radial glia may have to change from that of path‐defining cells to that of specialized precursor cells transiently fulfilling a guidance role during brain histogenesis, which probably constitutes one of the most common transdifferentiation events in mammalian development.

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Isolation of radial glial cells by fluorescent-activated cell sorting reveals a neuronal lineage.

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Cell lineage in the rat cerebral cortex: a study using retroviral-mediated gene transfer.

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