Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis.

@article{Haubensak2004NeuronsAI,
  title={Neurons arise in the basal neuroepithelium of the early mammalian telencephalon: a major site of neurogenesis.},
  author={Wulf E Haubensak and Alessio Attardo and W. Denk and W. Huttner},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 9},
  pages={
          3196-201
        }
}
  • Wulf E Haubensak, Alessio Attardo, +1 author W. Huttner
  • Published 2004
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • Neurons of the mammalian CNS are thought to originate from progenitors dividing at the apical surface of the neuroepithelium. Here we use mouse embryos expressing GFP from the Tis21 locus, a gene expressed throughout the neural tube in most, if not all, neuron-generating progenitors, to specifically reveal the cell divisions that produce CNS neurons. In addition to the apical, asymmetric divisions of neuroepithelial (NE) cells that generate another NE cell and a neuron, we find, from the onset… CONTINUE READING

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