Neurons Refine the Caenorhabditis elegans Body Plan by Directing Axial Patterning by Wnts

@inproceedings{Modzelewska2013NeuronsRT,
  title={Neurons Refine the Caenorhabditis elegans Body Plan by Directing Axial Patterning by Wnts},
  author={Katarzyna Modzelewska and Amara Lauritzen and Stefan Hasenoeder and Louise Jennifer Brown and John Georgiou and Nadeem Moghal},
  booktitle={PLoS biology},
  year={2013}
}
Metazoans display remarkable conservation of gene families, including growth factors, yet somehow these genes are used in different ways to generate tremendous morphological diversity. While variations in the magnitude and spatio-temporal aspects of signaling by a growth factor can generate different body patterns, how these signaling variations are organized and coordinated during development is unclear. Basic body plans are organized by the end of gastrulation and are refined as limbs, organs… CONTINUE READING
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