Neurons Controlling Aplysia Feeding Inhibit Themselves by Continuous NO Production

  title={Neurons Controlling Aplysia Feeding Inhibit Themselves by Continuous NO Production},
  author={Nimrod Miller and R. Ami Saada and Shlomi Fishman and Itay Hurwitz and Abraham J Susswein},
  booktitle={PloS one},
BACKGROUND Neural activity can be affected by nitric oxide (NO) produced by spiking neurons. Can neural activity also be affected by NO produced in neurons in the absence of spiking? METHODOLOGY/PRINCIPAL FINDINGS Applying an NO scavenger to quiescent Aplysia buccal ganglia initiated fictive feeding, indicating that NO production at rest inhibits feeding. The inhibition is in part via effects on neurons B31/B32, neurons initiating food consumption. Applying NO scavengers or nitric oxide… CONTINUE READING

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