Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice

@inproceedings{Millership2018NeuronatinDC,
  title={Neuronatin deletion causes postnatal growth restriction and adult obesity in 129S2/Sv mice},
  author={Steven J. Millership and Simon J. Tunster and Mathew Van de Pette and Agharul I. Choudhury and Elaine E Irvine and Mark Christian and Amanda G Fisher and Rosalind M John and James Brown Scott and Dominic J. Withers},
  booktitle={Molecular metabolism},
  year={2018}
}
OBJECTIVE Imprinted genes are crucial for the growth and development of fetal and juvenile mammals. Altered imprinted gene dosage causes a variety of human disorders, with growth and development during these crucial early stages strongly linked with future metabolic health in adulthood. Neuronatin (Nnat) is a paternally expressed imprinted gene found in neuroendocrine systems and white adipose tissue and is regulated by the diet and leptin. Neuronatin expression is downregulated in obese… CONTINUE READING
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