Neuronal subtype specification in the spinal cord of a protovertebrate.

  title={Neuronal subtype specification in the spinal cord of a protovertebrate.},
  author={Alberto Stolfi and Michael V Levine},
  volume={138 5},
The visceral ganglion (VG) comprises the basic motor pool of the swimming ascidian tadpole and has been proposed to be homologous to the spinal cord of vertebrates. Here, we use cis-regulatory modules, or enhancers, from transcription factor genes expressed in single VG neuronal precursors to label and identify morphologically distinct moto- and interneuron subtypes in the Ciona intestinalis tadpole larva. We also show that the transcription factor complement present in each differentiating… CONTINUE READING


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