Neuronal specification in the spinal cord: inductive signals and transcriptional codes

@article{Jessell2000NeuronalSI,
  title={Neuronal specification in the spinal cord: inductive signals and transcriptional codes},
  author={Thomas M. Jessell},
  journal={Nature Reviews Genetics},
  year={2000},
  volume={1},
  pages={20-29}
}
  • T. Jessell
  • Published 1 October 2000
  • Biology
  • Nature Reviews Genetics
Neural circuits are assembled with remarkable precision during embryonic development, and the selectivity inherent in their formation helps to define the behavioural repertoire of the mature organism. In the vertebrate central nervous system, this developmental program begins with the differentiation of distinct classes of neurons from progenitor cells located at defined positions within the neural tube. The mechanisms that specify the identity of neural cells have been examined in many regions… 
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