Neuronal signaling in central nervous system

@inproceedings{YouSheng2011NeuronalSI,
  title={Neuronal signaling in central nervous system},
  author={SHU You-Sheng},
  year={2011}
}
  • SHU You-Sheng
  • Published 2011
A new method of axon recording through axon bleb has boosted the studies on the functional role of central nervous system (CNS) axons. Using this method, we have revealed the mechanisms underlying the initiation and propagation of the digital-mode signal, all-or-none action potentials (APs), in neocortical pyramidal neurons. Accumulation of the low-threshold Na+ channel subtype Nav1.6 at the distal end of the axon initial segment (AIS) determines the lowest threshold for AP initiation, whereas… CONTINUE READING

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