Neuronal responses support a role for orbitofrontal cortex in cognitive set reconfiguration.

  title={Neuronal responses support a role for orbitofrontal cortex in cognitive set reconfiguration.},
  author={Brianna J. Sleezer and Giuliana A LoConte and Meghan D Castagno and Benjamin Y. Hayden},
  journal={The European journal of neuroscience},
  volume={45 7},
We are often faced with the need to abandon no-longer beneficial rules and adopt new ones. This process, known as cognitive set reconfiguration, is a hallmark of executive control. Although cognitive functions like reconfiguration are most often associated with dorsal prefrontal structures, recent evidence suggests that the orbitofrontal cortex (OFC) may play an important role as well. We recorded the activity of OFC neurons while rhesus macaques performed an analogue of the Wisconsin Card… CONTINUE READING
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