Neuronal protection and destruction by NO

  title={Neuronal protection and destruction by NO},
  author={Stuart Lipton},
  journal={Cell Death and Differentiation},
Nitric oxide (NO)-related species include different redox states of the NO group, which have recently been reported to exist endogenously in biological tissues including the brain. The importance of these different NO-related species is that their distinct chemical reactivities can influence the life and death of neurons in response to various insults. In the case of NO+ equivalents (having one less electron than NO.), the mechanism of reaction often involves S-nitrosylation or transfer of the… CONTINUE READING


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