Neuronal plasticity in relation to nociception and healing of rat achilles tendon.

@article{Ackermann2003NeuronalPI,
  title={Neuronal plasticity in relation to nociception and healing of rat achilles tendon.},
  author={Paul W Ackermann and Jian Li and Thomas Lundeberg and Andris Kreicbergs},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2003},
  volume={21 3},
  pages={432-41}
}
Nerve regeneration and the occurrence of three neuropeptides; i.e. substance P (SP), calcitonin gene related peptide (CGRP) and galanin (GAL), were studied during healing of tendon rupture in the rat by semi-quantitative immunohistochemistry. The neuronal findings were related to nociception as assessed by hindpaw withdrawal latencies at thermal and mechanical tests. Experimental rupture of rat Achilles tendon--normally devoid of nerves--elicited extensive nerve ingrowth into the rupture site… CONTINUE READING
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