Neuronal plasticity and pain

  title={Neuronal plasticity and pain},
  author={Ronald Dubner},
A frequent response to peripheral tissue damage or nerve injury is the appearance of constant pain, pain produced by innocuous stimulation, and increased sensitivity to noxious stimuli. The underlying pathophysiological mechanisms of these clinical features are poorly understood. Although peripheral neural mechanisms, such as nociceptor sensitization associated with tissue damage and neuroma formation following nerve injury, are contributors to the pathophysiology, recent studies indicate that… CONTINUE READING

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