Neuronal peptides induce oocyte maturation and gamete spawning of sea cucumber, Apostichopus japonicus.

  title={Neuronal peptides induce oocyte maturation and gamete spawning of sea cucumber, Apostichopus japonicus.},
  author={Shinichi Kato and Saori Tsurumaru and Makoto Taga and Tomoki Yamane and Yasushi Shibata and Kaoru Ohno and Atushi Fujiwara and Keisuke Yamano and Michiyasu Yoshikuni},
  journal={Developmental biology},
  volume={326 1},
Extracts prepared from tissues containing buccal ring nerve or longitudinal radial nerve of sea cucumber induce oocyte maturation and ovulation from ovarian tissues. We purified two small peptides, a pentapeptide and a heptapeptide, from the buccal tissues of Japanese common sea cucumber, Apostichopus japonicas. Both peptides induced oocyte maturation and gamete spawning. The pentapeptide was identified as NGIWYamide. This peptide induced in vitro germinal vesicle breakdown and ovulation of… CONTINUE READING


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