Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.

@article{Uno2006NeuronalPF,
  title={Neuronal pathway from the liver modulates energy expenditure and systemic insulin sensitivity.},
  author={Kenji Uno and Hideki Katagiri and Tetsuya Yamada and Yasushi Ishigaki and Takehide Ogihara and Junta Imai and Yutaka Hasegawa and Junhong Gao and Keizo Kaneko and Hiroko Iwasaki and Hisamitsu Ishihara and Hironobu Sasano and Kouichi Inukai and Hiroyuki Mizuguchi and Tomoichiro Asano and Masakazu Shiota and Masamitsu Nakazato and Yoshitomo Oka},
  journal={Science},
  year={2006},
  volume={312 5780},
  pages={1656-9}
}
Coordinated control of energy metabolism and glucose homeostasis requires communication between organs and tissues. We identified a neuronal pathway that participates in the cross talk between the liver and adipose tissue. By studying a mouse model, we showed that adenovirus-mediated expression of peroxisome proliferator-activated receptor (PPAR)-g2 in the… CONTINUE READING