Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury.

Abstract

Oxidative stress has emerged as a key deleterious factor in brain ischemia and reperfusion. Malfunction of the oxidative respiratory chain in mitochondria combines with the activation of cytoplasmic oxidases to generate a burst of reactive oxygen species that cannot be neutralised by the cell's antioxidant mechanisms. As a result, oxidative stress… (More)
DOI: 10.1016/j.neuint.2012.11.009

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@article{Manzanero2013NeuronalOS, title={Neuronal oxidative stress in acute ischemic stroke: sources and contribution to cell injury.}, author={Silvia Manzanero and Tomislav Santro and Thiruma Valavan Arumugam}, journal={Neurochemistry international}, year={2013}, volume={62 5}, pages={712-8} }