Neuronal osmotransduction: push-activating TRPV1 with microtubules.

Abstract

Regulating the osmotic pressure of our body fluids relies on osmosensory neurons that depolarize when their volume decreases. Recently in Neuron, Prager-Khoutorsky et al. (2014) report that this depolarization arises from direct interactions between the transient receptor potential channel TRPV1 and microtubules, which seem to directly push open the channel… (More)
DOI: 10.1016/j.devcel.2014.08.012

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@article{Andrs2014NeuronalOP, title={Neuronal osmotransduction: push-activating TRPV1 with microtubules.}, author={Marta Andr{\'e}s and Martin C. G{\"{o}pfert}, journal={Developmental cell}, year={2014}, volume={30 4}, pages={363-4} }