Neuronal nitric oxide synthase modulates rat renal microvascular function.

  title={Neuronal nitric oxide synthase modulates rat renal microvascular function.},
  author={Atsuhiro Ichihara and Edward W. Inscho and John D. Imig and Luis Gabriel Navar},
  journal={The American journal of physiology},
  volume={274 3 Pt 2},
This study was performed to determine the influence of neuronal nitric oxide synthase (nNOS) on renal arteriolar tone under conditions of normal, interrupted, and increased volume delivery to the macula densa segment and on the microvascular responses to angiotensin II (ANG II). Experiments were performed in vitro on afferent (21.2 +/- 0.2 microns) and efferent (18.5 +/- 0.2 microns) arterioles of kidneys harvested from male Sprague-Dawley rats, using the blood-perfused juxtamedullary nephron… CONTINUE READING
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