Neuronal nicotinic acetylcholine receptors: a new target site of ethanol

  title={Neuronal nicotinic acetylcholine receptors: a new target site of ethanol},
  author={T. Narahashi and G. Aistrup and W. Marszalec and K. Nagata},
  journal={Neurochemistry International},
  • T. Narahashi, G. Aistrup, +1 author K. Nagata
  • Published 1999
  • Chemistry, Medicine
  • Neurochemistry International
  • Whereas a variety of neuroreceptors and ion channels have been demonstrated to be affected by ethanol including GABAA receptors, NMDA receptors, non-NMDA glutamate receptors, 5-HT3 receptors and voltage-gated calcium channels, neuronal nicotinic acetylcholine receptors (nnAChRs) have recently emerged as a new target site of ethanol. The nnAChRs are different from the muscle type nicotinic AChRs with respect to their molecular architecture and pharmacology. This article briefly reviews the… CONTINUE READING
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